Powder one tablet and transfer to a 100-m1 volumetnc flask, add 60 ml of 0.1M hydrochlonc acid, and shake

obtained with solution (1) is not more intense than trie spot in the chromato gram obtained with solution (2) and not more than one such spot is more intense than the spot in the chromatogram obtained with solution (3J Uniformrty of content. Comply with the requirements stated under Tablets using the following method of analysis Powder one tablet and transfer to a 100-m1 volumetnc flask, add 60 ml of 0.1M hydrochlonc acid, and shake by mechanical means for 30 minutes. Dilute with 0 01 M hydrochlonc acid to volume, mix. and centrifuge a portion of the mixture Dilute an accurately measured portion of The clear supernatant liquid quantitatively to obtain a solution containing about 10 ug of amiloride hydrochlonde per ml. Measure the absorbance of the resulting solution at about 363 nm, Appendix 5 5 Calculate the content of C6 H8 CIN7 O takang 692 as the value of A(l %. 1 cm) at trie maximum at about 363 run. Other requirements Comphy with me requirements of tests staled under Tablets Assay Weigh and finefy powder 20 tablets Weigh accuratey a quantity of the powder equivalent to 10 mg of anhydrous amiloride hydrochlonde, transfer to a 100-m1 volumetric flask add 60 ml of 0 1M hyorochloric acid and complete the procedure described under Unrformity of content beginning at the words "and shake by mechanical means Calculate the content of C6 H8 CIN7 O, HCI taking 692 as the value of A(1 %, 1 cm) at the maximum at about 363 nmAMINOCAPROiC ACID NH2 CH2 CH2 CH2 CH2 CH2 COOHC6 H13 NO2 Mol Wt 131.17 Aminocaproic Acid rs B-ampnohexanoic acid Category Haemostatic; antifibnnolytic Dose Oralty and by slow intravenous infusion, initially 5 g followed by 1 to 1 25 g every hour until bleeding is under control, not more than 30 g per 24-hour period Description Colourless crystals or white, crystalline powder Solubility Freely soluble in water; slightly soluble in ethanol (95%) and in methanol